The church was erected by will of the City of Spoleto in 1527, a thanksgiving to the Virgin that supposedly spared the city from the Landsknecht who had just sacked Rome. Thanks to the protection of the Virgin, the city had escaped the danger and had actually prospered on trading with the invaders; the “golden manna” thus represented the sizeable profits the populace had enjoyed during the events.
Outside, the church presents a rectangular plant and a simple architecture, and features an octagonal tambour, possibly added later.
The inside has an octagonal plant with apsed presbytery and is the result of a late-17th-century remake.
A remarkable, big baptismal font, previously at the cathedral and dating to the first half of the 16th century, sticks out at the centre of the church, surrounded by canvases by 18th-century painter Sebastiano Conca.

AA.VV., L’Umbria, Manuali per il Territorio, Spoleto, Roma 1978